Endocrine Abstracts

High doses of anabolic-androgenic steroids (AAS), especially when taken concomitantly with multiple other preparations, can lead to a decrease in high-density lipoprotein (HDL) cholesterol and an increase in low-density lipoprotein (LDL) cholesterol. After long-term, high-dose AAS abuse, atherosclerosis may develop, leading to coronary artery disease, cerebral vascular disease or peripheral artery disease. The degree of atherosclerosis appears to be dependent on the duration o...

Background: The rare 46, XX-male syndrome has to be distinguished from more frequent forms of hypogonadism, especially the Klinefelter syndrome (47, XXY). We report 11 cases of SRY-positive XX-males in comparison to 101 age-matched Klinefelter patients and 78 age-matched normal men in a case-control study.Methods: The comparison included results from the physical examination, endocrinological data, semen analysis, cytogenetic and molecular genetic findin...